Can I run Minecraft Shaders smoothly with these computer specs?

CPU: AMD FX-6300 3.50 GHz Six-Core AM3+ CPU 6MB L2 Cache & Turbo Core Technology
Motherboard: * GIGABYTE 970A-DS3P AMD 970 ATX w/ Ultra Durable 4 Classic, On/Off Charge, GbLAN, 2 PCIe x16, 3 PCIe x1, 2 PCI
RAM: 8GB
Video Card: AMD Radeon R7 240 2GB GDDR3 PCIe 3.0 x16 Video Card (Single Card)
Power Supply: 550 Watts - XFX TS Series 80 PLUS BRONZE Certified Power Supply
Hard Drive: 2TB (2TBx1) SATA-III 6.0Gb/s 64MB Cache 7200RPM HDD (Single Drive)

Yes, with these computer specs you should be able to run shaders fine. If you want to be for sure you can look on CanYouRunIt? A website that compares your specs to the games minimum and recommended requirements too play. If all of your specs are a high percentile shaders should run fine. Have fun!

Yes it can, anything better than intel hd graphics in which their onbroad graphics the dedicated vram is lower than a dedicated gpu like the one you have uses almost all the vram for gaming